Franconian Longitudinal Study of Anorexia Nervosa in Adolescents - Basic Module

• Conditions: F50.0; F50.1; Anorexia nervosa; Atypical anorexia nervosa

• Registration Number: DRKS00024752
• Lead Sponsor: niversitätsklinikum Erlangen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-04-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 42

Inclusion Criteria

Anorexia Nervosa (AN) group: AN diagnosis according to ICD-10 criteria (F50.0 or F50.1), weight <10th BMI age percentile at start of participation; clinically depressed group (control group 1): diagnosis of a depressive disorder (F32.0-F32.2, F33) / adjustment disorder with depressive symptoms (F43.20-F43.22); healthy control group (control group 2): no diagnosis-worthy symptoms according to ICD-10 criteria. Control groups: BMI >10th age percentile.

Exclusion Criteria

Acute psychotic symptoms; substance abuse / addiction; chronic physiological conditions (especially cardiovascular diseases); medication with tranquillizing effects (such as Benzodiazepines); learning disabilities; insufficient German skills to give informed consent. For the control groups: eating disorders.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reaching a weight of BMI = 25th age percentile at discharge, keeping up the weight until a follow-up six months later.

Secondary Outcome Measures

Name	Time	Method
Eating disorder pathology, body dissatisfaction, movement patterns, heart rate and heart rate variability, biomarkers (leptin, ghrelin, NPY, PYY, IL-6, hsCRP, cortisol, alpha-amylase)