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Clinical Trials/NCT05557526
NCT05557526
Recruiting
Not Applicable

Optimizing Quality of Life by Improved Patient Expectation Following Atrial Fibrillation Catheter Ablation

Evangelical Hospital Düsseldorf3 sites in 1 country60 target enrollmentJune 9, 2022

Overview

Phase
Not Applicable
Intervention
Standard Medical Care Control Group
Conditions
Atrial Fibrillation
Sponsor
Evangelical Hospital Düsseldorf
Enrollment
60
Locations
3
Primary Endpoint
Quality of life (questionaire)
Status
Recruiting
Last Updated
4 days ago

Overview

Brief Summary

The aim is to investigate whether optimizing patients' expectations towards the interventional treatment of atrial fibrillation (catheter ablation) leads to a lower disease-related impairment of the patients compared to the control group in the first three months after ablation (the so-called blanking period).

Registry
clinicaltrials.gov
Start Date
June 9, 2022
End Date
December 1, 2027
Last Updated
4 days ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Evangelical Hospital Düsseldorf
Responsible Party
Principal Investigator
Principal Investigator

Christian Meyer

Head of the Division of Cardiology, Angiology and Intensive Care

Evangelical Hospital Düsseldorf

Eligibility Criteria

Inclusion Criteria

  • symptomatic atrial fibrillation
  • indication for pulmonary vein isolation
  • sufficient command of the German language

Exclusion Criteria

  • age \<18 years
  • permanent atrial fibrillation
  • presence of psychiatric disorders which impair the study participitatin
  • presence of another medical condiction which influences quality of life stronger than the cardiac condition
  • atrial fibrillation induced by intoxication, medicamentation or infection
  • inability to grap the course of the study

Arms & Interventions

Standard Medical Care Control Group

Patients with atrial fibrillation receiving catheter ablation of atrial fibrillation without additional intervention.

Optimize Expectation Group

Patients with atrial fibrillation receiving catheter ablation of atrial fibrillation and an additional verbal intervention to optimize the expectation of the patient towards the procedure.

Intervention: Expectation optimization

Outcomes

Primary Outcomes

Quality of life (questionaire)

Time Frame: 3 months

Quality of life of life will be compared between groups and between different time points (before versus 3 months after ablation) with "the atrial fibrillation effect on quality-of-life (AFEQT) questionnaire". An overall AFEQT score ranges from 0 to 100. A score of 0 corresponds to complete disability (or responding "extremely" limited, difficult or bothersome to all questions answered), while a score of 100 corresponds to no disability (or responding "not at all" limited, difficult or bothersome to all questions answered). Therefore, a positive change in score corresponds to improvement in AF symptoms.

Secondary Outcomes

  • Left ventricular ejection fraction [%](3 months)
  • Physical Activity (questionaire)(3 months, 12 months)
  • Autonomic function (heart rate variability measurement)(3 months)
  • Inflammatory markers from blood samples(3 months)
  • Treatment expectations (questionaire)(3 months, 12 months)
  • General quality of life (questionaire)(3 months, 12 months)
  • Hospital Anxiety and Depression Scale HADS (questionaire)(3 months, 12 months)
  • Recurrence of atrial arrhythmias(12 months)
  • Atrial volume [ml/m2](3 months)
  • Cardiac Anxiety Questionnaire CAQ (questionaire)(3 months, 12 months)
  • Recurrence of atrial arrhythmias(3 months)

Study Sites (3)

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