Comparison of the Effectiveness of Erector Spinae Plane Block Administered at Different Volumes on Postoperative Opioid Consumption and Analgesia in Patients Undergoing Total Abdominal Hysterectomy: A Randomized, Prospective, Double-Blind Study
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Şule Arıcan
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Total Morphine Consumption
Overview
Brief Summary
his study aims to investigate the effects of different volumes of ultrasound-guided erector spinae plane block (ESPB) on postoperative pain and opioid consumption in patients undergoing total abdominal hysterectomy. The researchers aim to determine whether varying the volume of local anesthetic in the ESPB can reduce the amount of morphine required by patients and improve pain scores during the first 24 hours after surgery.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients aged between 18 and 65 years.
- •Patients with American Society of Anesthesiologists (ASA) physical status I-III.
- •Patients scheduled to undergo elective total abdominal hysterectomy surgery.
Exclusion Criteria
- •Obese patients (Body Mass Index \> 30 kg/m²).
- •Patients with local skin infection at the site of needle insertion.
- •Patients with a known allergy to any of the medications used in the study.
- •Patients with coagulopathy.
- •Patients with chronic opioid consumption.
- •Patients with an inability to use the Patient-Controlled Analgesia (PCA) device.
- •Patients with advanced hepatic or renal failure.
- •Patients who refuse to participate in the study.
Arms & Interventions
Group I
Patients in Group I received a preoperative bilateral ultrasound-guided erector spinae plane block (ESPB) with 20 ml of 0.25% bupivacaine hydrochloride (prepared by combining 10 ml of 0.5% bupivacaine hydrochloride with 10 ml of saline) for each side.
Intervention: Erector Spinae Plane Block (Procedure)
Group II
Patients in Group II received a preoperative bilateral ultrasound-guided erector spinae plane block (ESPB) with 30 ml of 0.25% bupivacaine hydrochloride (prepared by combining 15 ml of 0.5% bupivacaine hydrochloride with 15 ml of saline) for each side.
Intervention: Erector Spinae Plane Block (Procedure)
Outcomes
Primary Outcomes
Total Morphine Consumption
Time Frame: First 24 hours postoperatively
The total amount of morphine (in milligrams) consumed by the patient via the Patient-Controlled Analgesia (PCA) device.
Secondary Outcomes
- Numerical Rating Scale (NRS) Scores for Pain(At postoperative 30 minutes, 2nd, 6th, 12th, and 24th hours)
- Number of Blocked Dermatomes(20 minutes after the block procedure)
Investigators
Şule Arıcan
Associate Professor
Konya Necmettin Erbakan Üniversitesi