Effect of Cavotricuspid Isthmus Ablation in Patients Without History of Typical Flutter During Ablation

Not Applicable

Completed

• Conditions: Paroxysmal Atrial Fibrillation
• Interventions: Procedure: cavotricuspid isthmus ablation; Procedure: control group

• Registration Number: NCT02031705
• Lead Sponsor: Yong Seog Oh

Brief Summary

It has been demonstrated that successful cavotricuspid isthmus ablation may be effective in preventing paroxysmal atrial fibrillation. However, the effectiveness of only isthmus ablation on atrial fibrillation itself is unclear.

Detailed Description

Researchers hypothesized that an organized activation pattern around the tricuspid annulus during atrial fibrillation indicated a mother reentrant circuit that could be terminated by a cavocaval isthmus ablation, thus preventing atrial fibrillation. The objectives of the present study were to evaluate the effectiveness of isthmus ablation in preventing atrial fibrillation and to identify predictors of its success.

Study Timeline

• Study Start: 2012-07
• Study First Submitted: 2013-09-09
• Study First Submitted QC: 2014-01-08
• Study First Posted: 2014-01-09
• Primary Completion: 2019-06
• Study Completion: 2019-08
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-21
• Last Update Posted: 2024-04-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 366

Inclusion Criteria

• Scheduled ablation for paroxysmal atrial fibrillation

Exclusion Criteria

• Typical atrial flutter
• History of artificial tricuspid valve surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
cavotricuspid isthmus ablation	cavotricuspid isthmus ablation	Isthmus ablation was performed in paroxysmal atrial fibrillation patients.
control group	control group	Control group was performed no additional cavotricuspid isthmus ablation.

Primary Outcome Measures

Name	Time	Method
Freedom of AF and Af	1 year after catheter ablation	1 month, 3 months and 12months after ablation follow up visit and Check the recurrence of atrial fibrillation through EKG,Holter, event recording

Trial Locations

Locations (1)

Seoul st. mary's hospital; 🇰🇷 Seoul, Korea, Republic of