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临床试验/DRKS00010456
DRKS00010456已完成未知

Benefit of oocyte activation with GM508 CultActive in an IVF/ICSI therapy with different clinical pictures of sub- or infertility. A prospective – randomized pilot study. - GM508 CultActive in IVF/ICSI therapy

IVF Zentren Prof. Zech0 个研究点目标入组 532 人开始时间: 2016年4月27日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
532

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomized controlled study
盲法
Blinded (masking used)

入排标准

年龄范围
18 Years 至 43 Years(—)
性别
All

入选标准

  • All IVF couples with indications for artificial oocyte activation that have signed an informed consent before therapy.
  • Indications are:
  • Male sub- or infertility including oligoasthenoteratozoospermia of different grades and obstructive and non-obstructive azoospermia including cycles with fertilization after testicular sperm extraction (TESE)
  • Couples with reduced fertilization rate after ICSI, but potentially normal spermiocytogram, as well as patients with observed reduced embryonic cleavage rate or reduced blastocyst rate after ICSI.

排除标准

  • Less than 2 mature (MII) oocytes after retrieval
  • female age =44 Years (no age restrictions for males )
  • known chromosomal abberations of one or both partners
  • egg donnation patients
  • Patients with total globozoospermia (therefore oocyte activation is obligate)

研究者

发起方
IVF Zentren Prof. Zech

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