A comparative study on clinical efficacy of Topical Tofacitinib 2 percent cream versus Topical Calcipotriol 0.005 percent ointment in the treatment of Alopecia Areata
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To assess and compare the efficacy of topical tofacitinib cream (2%) and topical calcipotriol ointment (0.005%) in promoting hair regrowth and minimizing disease progression in individuals with alopecia areata
研究概览
简要总结
A total of 100 patients of alopecia areata visiting dermatology OPD of Era’s Lucknow Medical College and Hospital fulfilling inclusion will be enrolled in our study.
•Written informed consent will be taken from patients prior to participation in study.
•Patients will be randomly divided into two groups - group A and group B each containing 50 individuals.
•Detailed history and clinical examination12of the scalp with photographic documentation and subjective response will be noted before the start of the treatment and then at each visit (4,8,12 and 16 weeks) and results will be tabulated in respective tables.
1.In group A –
Each patient will be advised tofacitinib cream (2%) twice daily application over the affected area for 12 weeks with follow up at every 4th, 8th, 12th and 16th week.
- In group B-
Each patient will be advised calcipotriol ointment (0.005%) twice daily application over the affected area for 12 weeks with follow up at every 4th, 8th, 12th and 16th week .
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •All consenting patients of alopecia areata with SALT score less than 25% scalp involvement of either gender aged 18 years and above visiting in Dermatology OPD.
排除标准
- •Patients who have taken any form of treatment in past 3 months Immunocompromised patients or patients on immunosuppressive therapy will be excluded Pregnant or lactating mothers Patient with a history of hypersensitivity to tofacitinib or calcipotriol.
结局指标
主要结局
To assess and compare the efficacy of topical tofacitinib cream (2%) and topical calcipotriol ointment (0.005%) in promoting hair regrowth and minimizing disease progression in individuals with alopecia areata
时间窗: 4 weeks,8 weeks,12 weeks, 16 weeks
次要结局
- To analyse the efficacy of tofacitinib cream (2%) in alopecia areata.
研究者
DR NEHA KHAN
ERA S LUCKNOW MEDICAL COLLEGE AND HOSPITAL