A Randomized Comparative Study Of Ropivacaine Vs Ropivacaine With Dexamethasone In Ultrasound Guided Pericapsular Nerve Group Block For Preoperative and Postoperative Analgesia In Patients Undergoing Elective Hip Surgery SMS Medical College, Jaipur..
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- 1.To asses and compare NRS after giving PENG block between both the groups before positioning for spinal anesthesia.
研究概览
简要总结
Hip fractures are common orthopedic problems associated with significant morbidity and
mortality. As a definitive treatment, most patients with fractured hips would undergo early
reduction and surgical fixation (1). The majority of hip fractures in the elderly population
results from an inadvertent fall, whereas, it is more commonly caused due to a high energy
trauma in the younger and adult population (2). Irrespective of the etiology, hip fractures are a
painful condition, and early pain relief and definitive management is of utmost importance,
especially in the elderly population.
Hip surgery is often accompanied by severe pain-induced postoperative adverse effects, such
as enhanced blood pressure, delayed mobility, delirium, and deep vein thrombosis. As a
result, patients require large opioid doses for pain relief, which, in turn, induce drug-related
complications like nausea, vomiting, itching, and respiratory inhibition, which are not
conducive to patient recovery. (3)
Central neuraxial blockade is the most common anaesthetic technique for hip surgical
procedures. Patients with hip fracture experience excruciating pain, which would prevent the
ideal positioning of the patient for the neuraxial blockade . (4) There is growing interest in using
regional nerve blocks for pain reduction in the elderly with fractured hip. Femoral nerve
block (FN), Fascia Iliaca block (FIB), and 3-in-1 FN block were formerly used to treat hip
fractures. These blocks provided perioperative analgesia and reduced the patient’s
postoperative opioid requirement . (5) Although FNB and FICB provides adequate analgesia for
patients, it has certain limitations, such as incomplete block and lower limb muscle weakness.
The anterior capsule of the hip joint is mainly supplied by branches of the femoral nerve
(FN), obturator nerve (ON), and accessory obturator nerve (AON). Literature suggests that
the obturator nerve is not covered in these blocks. The core of hip analgesia is the anterior
capsule, and FN, ON, and AON are the keys to block (6) PENG, a new regional block
technique introduced by Girón Arango et al. (7) in 2018.Available evidence suggests that the
PENG block has shown some promise in cases undergoing hip surgery . (8) We have planned
this study to compare the pre operative and post operative analgesic efficacy of USG guided
PENG block with Ropivacaine vs Ropivacaine with Dexamethasone for elective hip surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •Patient undergoing elective surgery for hip fracture under spinal anesthesia.
- •Patients consenting to participate.
- •Adult patients.
- •Patients belonging to American Society of Anesthesiologists (ASA) grade I, II and III.
排除标准
- •Patients participating in other study Uncooperative patients Patients with psychiatric illness Patients with peripheral sensorineural deï¬cit.
- •Patients allergic to local anesthetics.
- •Infection at the site of block Patients with contraindications to regional anaesthesia.
- •Patients with suspected compartment syndrome in lower limbs.
结局指标
主要结局
1.To asses and compare NRS after giving PENG block between both the groups before positioning for spinal anesthesia.
时间窗: 1.To asses and compare Numerical rating scale (NRS) score in postoperative period at 30minute,1,2,4,6,12,18, and 24 hr. between both the groups | 2.To determine the difference in mean dose of analgesic required for 24 hours in both groups.
2.To asses and compare total duration of analgesia between both the groups.
时间窗: 1.To asses and compare Numerical rating scale (NRS) score in postoperative period at 30minute,1,2,4,6,12,18, and 24 hr. between both the groups | 2.To determine the difference in mean dose of analgesic required for 24 hours in both groups.
次要结局
- 1.To determine the change in the hemodynamic parameters (HR, SBP, DBP, MAP and SpO2) in both groups.(2.To assess and compare patient satisfaction using Three-Point Likert Rating Scale between both groups.)
研究者
Dr Mamta Khandelwal
SMS Medical College and Hospital
