NCT00674232已完成不适用
Misoprostol for Treatment of Incomplete Abortion
Gynuity Health Projects3 个研究点 分布在 2 个国家目标入组 311 人开始时间: 2006年5月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 311
- 试验地点
- 3
- 主要终点
- complete resolution of signs/symptoms of incomplete abortion without recourse to surgery at any point for any reason
研究概览
简要总结
This study aims to compare the efficacy, side effects profile and acceptability of a single dose of 600mcg misoprostol taken orally compared to standard surgical treatment as per local protocols for the treatment of incomplete abortion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 —（Child, Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •past or present history of vaginal bleeding during pregnancy
- •open cervical os
- •evidence of incomplete abortion with substantial debris in the uterus (if using ultrasound)
- •surgical evacuation of the uterus would be advised as course of action if misoprostol was not available
- •generally in good health
- •woman lives or works within one hour of study site
- •woman willing to provide contact information for follow up purposes
- •informed consent given
排除标准
- •contraindications to study drug
- •uterine size larger than 12 weeks LMP
- •signs of severe infection
研究组 & 干预措施
Misoprostol
Experimental
Group 1 randomized to take single dose of 600 mcg oral misoprostol
干预措施: 600 mcg misoprostol (Drug)
Surgical treatment
Other
Group 2 randomized to receive standard surgical treatment as per local protocol (D&C or MVA)
干预措施: Surgical treatment (Procedure)
结局指标
主要结局
complete resolution of signs/symptoms of incomplete abortion without recourse to surgery at any point for any reason
时间窗: one week after initial treatment
次要结局
- side effects(measured at follow up visit one week after initial treatment)
- acceptability(measured at follow up visit one week after initial treatment)
研究者
研究点 (3)
Loading locations...
相似试验
已完成
不适用
Sublingual Misoprostol for the Treatment of Incomplete Abortion: Operations ResearchIncomplete AbortionNCT02707653Gynuity Health Projects75
已完成
不适用
Misoprostol for the Treatment of Incomplete AbortionAbortion, IncompleteNCT00670761Gynuity Health Projects720
已完成
不适用
The effect of misoprostol with folley catheter (traction) & Rising induction in second trimester terminatioIRCT201103146066N1Vice chancellor for research, Hamedan University of Medical Sciences72
已完成
3 期
A clinical trial to study the effects of mifepristone and misoprostol given at same time for abortion.CTRI/2010/091/001422I100
招募中
不适用
Investigation of the effect of misoprostol in comparison with misoprostol with Foley catheter on cervical ripening for labor induction of in women with preterm premature rupture of the membranePreterm premature rupture of the membranes.Premature rupture of membranesIRCT20181123041731N1Mashhad University of Medical Sciences200