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Effects of Exercise Training with Blood Flow Restriction

Not Applicable
Completed
Conditions
Healthy
Interventions
Other: Low Load Blood Flow Restriction Exercise Training (LL-BFRE)
Other: High Load Resistive Exercise Training (HL-RE)
Registration Number
NCT06507501
Lead Sponsor
Atlas University
Brief Summary

In this study, it was aimed to compare the effects of low load blood flow restriction exercise (LL-BFRE) training versus high load resistance exercise (HL-RE) training in healthy young individuals on the parameters of lower extremity muscle strength, dynamic and static postural balance, functional performance and cognitive performance.

Detailed Description

In this randomized controlled study, there will be two study group. Study group 1 will recieve low load blood flow restriction exercise training and Study group 2 will recieve high load resistance exercise training for 6 weeks, 2 exercise sessions weekly.

At baseline assessment, individuals who met the inclusion criteria, informed by the researcher and accept the participate in the study, researcher will record the participants' sociodemographic and physical informations and then, asess the lower extremity muscle strength with Hand-held digital dynamometer, dynamic postural balance with Y-Balance Test-Lower Quarter, static postural balance with Single Leg Stance Test (Eyes open/closed condition), functional performance with 6-Minute Walking Test and cognitive performance with Stroop Word and Colour Test and Trail Making Test.

At the end of the 6 week exercise training all participants will undergo the same assessments.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Volunteering to participate in the study,
  • Being between the ages of 18-30.
Exclusion Criteria
  • Presence of any painful condition or pathology involving the lower extremity and lumbar spine and the presence of a surgical history,
  • Presence of serious malalignment and deformity affecting the lower extremity,
  • Presence of neuromuscular and metabolic disease,
  • Presence of any disease affecting lower extremity circulation,
  • Having a history of deep vein thrombosis and the presence of peripheral vascular disease,
  • Presence of endothelial dysfunction (ED) and any disease that may cause ED,
  • Presence of active infection, cancer and having received radiotherapy / chemotherapy,
  • Continuous use of anticoagulant medication,
  • Having had COVID-19 in the last 3 months or having long COVID syndrome,
  • Presence of a cognitive or mental disorder that would disability to participate in the study,
  • Disruption of exercise program 3 times in a row

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Blood Flow Restriction Exercise Training (BFRT)Low Load Blood Flow Restriction Exercise Training (LL-BFRE)Exercises will be performed under the supervision of a researcher physiotherapist, at low intensity and progressively, under blood flow restriction for 6 weeks, 2 days a week, for a total of 12 exercise sessions. The 1 MT method will be used to determine the amount of resistance in strengthening exercises. Blood flow restriction will be made by wearing a pneumatic tourniquet from the proximal thigh, within a safe pressure range specific to each individual. Blood flow restriction United States Food and Drug Administration Using the (FDA) approved H+Cuff device, it will be applied for 20 minutes, with a 1-minute break between exercises. The cuff pressure will be maintained during the rest period, and after the application, individuals will rest for 15 minutes to ensure reperfusion and other exercises will continue.
Conventional Exercise TrainingHigh Load Resistive Exercise Training (HL-RE)Participants who will be included in the conventional exercise group will apply the same exercise program as the participants in the blood flow-restricted exercise group, without blood flow restriction, for 6 weeks, 2 days a week, in a total of 12 sessions, at medium-high intensity.
Primary Outcome Measures
NameTimeMethod
Dynamic BalanceBaseline to 6 weeks after exercise training

Dynamic balance will be assessed by using Y-Balance Test Lower Extremity.

Static BalanceBaseline to 6 weeks after exercise training

Static balance will be assessed by using Single Leg Stance Test with eyes open and closed.

Muscle StrengthBaseline to 6 weeks after exercise training

Knee extansor and flexor muscle strength will be measured by using Hoggan Scientific; MicroFET2 brand hand-held dynamometer.

Secondary Outcome Measures
NameTimeMethod
Funtional PerformanceBaseline to 6 weeks after exercise training

Functional performance will be assessed by using Single Leg Hop Test.

Cognitive PerformanceBaseline to 6 weeks after exercise training

Cognitive performance will be assessed by using Stroop Colour and Word Test.

Trial Locations

Locations (1)

Onur Turan

🇹🇷

Istanbul, Kağıthane, Turkey

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