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Clinical Trials/NCT01457651
NCT01457651
Completed
Not Applicable

Comparison of Different Types of Postoperative Pulmonary Recruitment and Predicting Its Efficacy Following Off-pump Coronary Artery Bypass Grafting

Northern State Medical University1 site in 1 country76 target enrollmentMarch 2010
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ConditionsHypoxemiaRecruitment

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hypoxemia
Sponsor
Northern State Medical University
Enrollment
76
Locations
1
Primary Endpoint
Respiratory support
Status
Completed
Last Updated
12 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The risk of respiratory failure after cardiac surgery is high, and it may result in many complications. The maneuver of alveolar recruitment may improve the oxygen transport in the human organism. The investigators compare three different types of alveolar recruitment in patient after cardiac surgery, to reveal which one is better.

Detailed Description

The study compares three different approaches to alveolar recruitment maneuvers in the immediate postoperative period after off-pump coronary bypass grafting.

Registry
clinicaltrials.gov
Start Date
March 2010
End Date
January 2012
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Northern State Medical University
Responsible Party
Principal Investigator
Principal Investigator

Vsevolod V. Kuzkov

Associate Professor, MD, PhD

Northern State Medical University

Eligibility Criteria

Inclusion Criteria

  • •Age between 18 and 75
  • •Off-pump coronary artery bypass grafting
  • •Possibility to discontinue respiratory support in the first day after intervention

Exclusion Criteria

  • •Signs of ARDS
  • •COPD in decompensation phase
  • •Requirement for inotropic support(epinephrine \>0,1 mcg/kg/hr)
  • •Bronchiectases
  • •Pregnancy
  • •Morbid obesity
  • •Aortic aneurism
  • •AMI in previous month

Outcomes

Primary Outcomes

Respiratory support

Time Frame: 24 hrs

The duration of the postoperative respiratory support

Secondary Outcomes

  • The incidence of postoperative atelectasis(24 hrs)
  • Incidence of reintubation(24 Hrs)
  • Oxygenation(12 hrs after extubation)
  • Length of ICU and hospital stay(28 Days)

Study Sites (1)

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