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Children receiving Heliox Inhalation in Croup: a randomised controlled trial

Completed
Conditions
Croup (laryngotracheobronchitis)
Respiratory
Registration Number
ISRCTN82240782
Lead Sponsor
niversity Hospitals of Leicester NHS Trust (UK)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
142
Inclusion Criteria

Children, aged six months to five years, presenting to the Emergency Department (ED) with moderate to severe croup (Modified Westley Croup Score of two or more).

Exclusion Criteria

1. Children whose oxygen saturation is less than 95%
2. Children with known pre-existing lung or airway disease, congenital heart disease, or features suggesting other causes of stridor, such as peritonsillar abscess, epiglottitis or inhaled foreign body

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Modified Westley Croup Score at 30 minutes
Secondary Outcome Measures
NameTimeMethod
1. Croup score at 15 minutes<br>2. Respiratory rate at 15, 30 minutes<br>3. Parents assessment of change on Visual Analog Scale<br>4. Number of epinephrine nebulisers given<br>5. Requirement for supplemental oxygen therapy<br>6. Admission to hospital<br>7. Intubation rate <br>8. Length of stay in ED<br>9. Length of stay in hospital<br>10. Subsequent use of health services
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