Descemet Membrane Endothelial Keratoplasty (DMEK)

Not Applicable

Completed

• Conditions: Corneal Dystrophies, Hereditary
• Interventions: Procedure: Descemet Membrane Endothelial Keratoplasty (DMEK)

• Registration Number: NCT00521898
• Lead Sponsor: Netherlands Institute for Innovative Ocular Surgery

Brief Summary

To evaluate isolated Descemet membrane transplantation as a refinement of previous advanced techniques for corneal transplantation, like Descemet Stripping Endothelial Keratoplasty (DSEK)

Detailed Description

See above.

Study Timeline

• Study Start: 2005-02
• Study First Submitted: 2007-08-24
• Study First Submitted QC: 2007-08-24
• Study First Posted: 2007-08-28
• Primary Completion: 2020-02
• Study Completion: 2020-02
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-11
• Last Update Posted: 2023-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Corneal endothelial disorders

Exclusion Criteria

• N/A

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
DMEK	Descemet Membrane Endothelial Keratoplasty (DMEK)	DMEK as intervention

Primary Outcome Measures

Name	Time	Method
Best spectacle corrected visual acuity	2005-2015

Secondary Outcome Measures

Name	Time	Method
Corneal endothelial cell density	2005-2015

Trial Locations

Locations (1)

Netherlands Institute for Innovative Ocular Surgery; 🇳🇱 Rotterdam, Netherlands