ISRCTN88729946
Completed
Not Applicable
Treatment of acute hepatitis C infection: immediate therapy of all patients with peg-interferon alpha-2b alone versus delayed therapy of patients not eliminating hepatitis C virus (HCV) spontaneously with peg-interferon alpha-2b plus ribaviri
Hannover Medical School (Medizinische Hochschule Hannover) (Germany)0 sites135 target enrollmentSeptember 9, 2005
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute hepatitis C
- Sponsor
- Hannover Medical School (Medizinische Hochschule Hannover) (Germany)
- Enrollment
- 135
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients with acute HCV infection and detectable HCV RNA
- •2\. More than 18 years
- •3\. Compensated liver disease
- •4\. Negative urine or blood pregnancy test
- •5\. Willingness to give written informed consent
Exclusion Criteria
- •1\. Other possible reasons for acute HCV infection
- •2\. Liver cirrhosis
- •3\. Pregnancy or breast feeding
- •4\. Previous antiviral therapy with interferon or ribavirin
- •5\. Positive test results for anti hepatitis A virus (HAV) IgM antib., HBsAg, anti\-HBc IgM antib., HBeAg, anti human immunodeficiency virus (HIV)
- •6\. History or evidence for chronic liver disease
- •7\. History of severe psychiatric disease, thyroid dysfunction poorly controlled
- •8\. History or evidence for severe illness
- •9\. Drug use within 6 mionths prior to first dose of study drug
Outcomes
Primary Outcomes
Not specified
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