Effects of Trans-resveratrol on Cognitive Performance in Healthy, Young Humans: a Double-blind, Placebo-controlled, Crossover Investigation.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Number of participants with altered cognitive function at 40mins post-dose
研究概览
简要总结
This study investigated the potentially cognitive enhancing effects of 500mg trans-resveratrol in healthy, young humans.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-35yrs, healthy.
排除标准
- •Drug/alcohol abuse, taking prescription medication (apart from contraception) or herbal supplements, having food intolerances or allergies, having suffered a head-injury or neurological/neuro-developmental disorder, uncorrected sight problems, pregnant or seeking to become so, excessive caffeine use (e.g. more than 6 cups of coffee per day).
结局指标
主要结局
Number of participants with altered cognitive function at 40mins post-dose
时间窗: 40mins Post-dose
This outcome measure is assessed by the number of participants whose scores on a range of cognitive tasks (word and picture recall and recognition, serial 3s and 7s subtractions, rapid visual information processing (RVIP), N-Back (3-Back version), Stroop and numeric working memory) differed from the baseline to 40min post-dose scores.
Number of participants with altered cognitive function at 2.5hrs post-dose
时间窗: 2.5hrs post-dose
This outcome measure is assessed by the number of participants whose scores on a range of cognitive tasks (word and picture recall and recognition, serial 3s and 7s subtractions, rapid visual information processing (RVIP), N-Back (3-Back version), Stroop and numeric working memory) differed from baseline to the 2.5hr post-dose scores.
Number of participants with altered cognitive function at 4hrs post-dose
时间窗: 4hrs post-dose
This outcome measure is assessed by the number of participants whose scores on a range of cognitive tasks (word and picture recall and recognition, serial 3s and 7s subtractions, rapid visual information processing (RVIP), N-Back (3-Back version), Stroop and numeric working memory) differed from baseline to the 4hr post-dose scores.
Number of participants with altered cognitive function at 6hrs post-dose
时间窗: 6hrs post-dose
This outcome measure is assessed by the number of participants whose scores on a range of cognitive tasks (word and picture recall and recognition, serial 3s and 7s subtractions, rapid visual information processing (RVIP), N-Back (3-Back version), Stroop and numeric working memory) differed from baseline to the 6hr post-dose scores.
次要结局
- Number of participants with altered mood at 40mins post-dose.(40mins post-dose)
- Number of participants with altered mood at 2.5hrs post-dose(2.5hrs post-dose)
- Number of participants with altered mood at 4hrs post-dose(4hrs pos-dose)
- Number of participants with altered mood at 6hrs post-dose(6hrs post-dose)
研究者
David Kennedy
Professor
Northumbria University