The Influence of Oral Probiotic on the Vaginal Flora and Microenvironment Alteration in the Vaginosis Infection Women
Not Applicable
Recruiting
- Conditions
- Probiotic, Human Papillomavirus Infection, Pap Smear, Microbiome
- Registration Number
- NCT06001190
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
A single-blind, randomized, and probiotic-treatment including adult women with vaginitis and/or HPV positive. After oral probiotics, all participants will be followd-up cervical swabs and vaginal microbiome alteration till the end of the study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 76
Inclusion Criteria
- diagnosed as vaginal viginitis
- willing to sign permit
- willing to regular follow up
Exclusion Criteria
- Pregnant
- Virgin
- Severe cervix pathology CINII or CIN III
- Confirmed cervical cancer
- under long term antibiotics due to other physical condition
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method improvement alteration of vaginal microbiome 3 months 16s rRNA
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kaohsiung Chang Gung Memorial Hospital
🇨🇳Kaohsiung, Taiwan