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Clinical Trials/NCT01258465
NCT01258465
Completed
N/A

Research in Autism: Parent Intervention

University of California, San Diego2 sites in 1 country39 target enrollmentJanuary 2005

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autistic Disorder
Sponsor
University of California, San Diego
Enrollment
39
Locations
2
Primary Endpoint
Mullen Scales of Early Learning
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model. In one condition, randomly assigned children were provided with an intervention that typically results in acquisition of expressive words in a large percentage of children diagnosed as having autism, using a well-documented manualized intervention focused on verbal expressive communication only (Pivotal Response Training, PRT). In the other condi¬tion, randomly assigned children received a widely used intervention on the same social communication functions using a well-documented manualized augmentative system of intervention (Picture Exchange Communica¬tion System, PECS) that has been reported to produce verbal and nonverbal communication in large percentages of children diagnosed with autism. Children in the two conditions were compared for development of verbal and nonverbal communication, changes in disruptive behavior, changes in symptoms of autism, and general adaptive behavior gains. In addition, parent satisfaction and stress measures were gathered in order to assess the effects of each intervention on family functioning.

Registry
clinicaltrials.gov
Start Date
January 2005
End Date
December 2009
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of Autistic Disorder or At Risk of Autistic Disorder
  • Age 2-0 to 3-11 years of age
  • Use of fewer than 10 functional words at intake

Exclusion Criteria

  • Primary diagnosis of mental retardation
  • Neurologic pathology (e.g., PKU, encephalitis, brain trauma)
  • Major sensory impairment

Outcomes

Primary Outcomes

Mullen Scales of Early Learning

Time Frame: 23 weeks with three months follow-up

Secondary Outcomes

  • Vineland Adaptive Behavior Scales(23 weeks and 3 month follow up)

Study Sites (2)

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