Efficacy of maggot therapy on Staphilococcus aureus and Pseudomonas aeruginosa in diabetic foot ulcers
- Conditions
- Chronic ulcer of skin, not elsewhere classified.Chronic ulcer of skin NOS
- Registration Number
- IRCT2016060328232N1
- Lead Sponsor
- Vice Chancellor of Research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
patients with at least one diabetic foot ulcer, second degree (based on Wagner); Presence of at least one of two bacteria (Staphilococcus aureus and Pseudomonas aeruginosa) in the ulcers, patient's age between 30 to 80; At least seven week post ulceration; having ankle-brachial index (ABI) more than 0.6 or two clear beats on ulcerated leg; not need to be hospitalized; lack of other dangerous diseases; no need for anticoagulant or steroid pharmaceutics; ?not addicted to alcohol or opium; no entomophobia; to sign the consent.
Exclusion criteria: Having sever diseases such as heart disorders and so on, Sever pain during maggot Therapy, Sever and un-controlled fever during maggot therapy, maceration around the wound after each interval of maggot therapy, Emergent hospitalization during or after of each interval of maggot therapy, Bleeding during maggot therapy
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ?acterial infections, Staphilococcus aureus and Pseudomonas aeruginosa. Timepoint: sampling before starting of the study and 48 and 96 hours after starting of the study. Method of measurement: culturing of samples in laboratory.
- Secondary Outcome Measures
Name Time Method Amounts of wound secretions. Timepoint: 48 and 96 hours after starting of the study. Method of measurement: befors/after weighing of dressings of diabetic foot ulcers of both groups, treatment and control, synchronizingly.