跳至主要内容
临床试验/NCT05550012
NCT05550012尚未招募不适用

Evaluation of a New Deep-learning Based Artificial Intelligence Iterative Reconstruction (AIIR) Algorithm in Different Enhancement Phases of Low-dose Liver CT

Qianfoshan Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年9月30日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
contrast to noise ratio (CNR)

研究概览

简要总结

CT-enhanced scans are routine imaging modality for the diagnosis and follow-up of liver disease. However, this means that patients will receive more radiation dose. Therefore, it is necessary to reduce the radiation dose received by patients as much as possible. Deep learning-based reconstruction algorithms have been introduced to improve image quality recently. For many years, researchers attempt to maintain image quality using an advanced method while reducing radiation dose. Recently, a new deep-learning based iterative reconstruction algorithm, namely artificial intelligence iterative reconstruction (AIIR, United Imaging Healthcare, Shanghai, China) has been introduced. In this study, we evaluate the image and diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT.

详细描述

In our hospital, patients with abdominal pelvic cancer undergo follow-up low-dose CT for the evaluation of treatment plan after clinical treatment or disease progress. The raw-data of low-dose CT were collected retrospectively and reconstructed using KARL and AIIR algorithm. In this study, we evaluate the image and diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • those scheduled for contrast-enhanced liver CT

排除标准

  • images affected by artifacts (motion or implants)

结局指标

主要结局

contrast to noise ratio (CNR)

时间窗: 6 months

Evaluate the image qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT

diagnostic confidence

时间窗: 6 months

Evaluate the diagnostic qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT

signal-to-noise ratio (SNR)

时间窗: 6 months

Evaluate the image qualities of AIIR for low-dose portal vein and delayed phase liver CT with those of a KARL method normally used in standard-dose CT

次要结局

未报告次要终点

研究者

发起方
Qianfoshan Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Qingshi Zeng

Clinical Professor

Qianfoshan Hospital

研究点 (1)

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