A retrospective study to assess the effectiveness and safety of lactulose retention enema in the treatment of cirrhotic patients with grade 3 or 4.
- Conditions
- Health Condition 1: null- cirrhotic patients with grade 3 or 4 (West Haven Criteria) hepatic encephalopathy (HE)
- Registration Number
- CTRI/2016/09/007260
- Lead Sponsor
- Abbott India Linited
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 50
1 Patients aged between 18 and 65 years of either gender
2 Patients admitted to the hospital with liver cirrhosis and grade 3 or grade 4 (West Haven Criteria) HE
3 Patients treated with lactulose retention enema within 48 hours of onset of grade 3 or 4 (West Haven Criteria) HE
1. Patients treated with agents other than lactulose retention enema for grade 3 or 4 (West Haven Criteria) HE.
2 Patients who had significant concomitant diseases that could impair or contribute to the impairment of consciousness
3 Patients who had a major neuropsychiatric illness
4 Patients who had a contraindication to lactulose, including Hypersensitivity to the active substance or to any of the ingredients Galactosaemia Gastrointestinal obstruction digestive perforation or risk of digestive perforation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method