Detection of Coronary Artery Disease Using Analysis of High Frequency QRS: The HyperQ Registry
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- BSP Biological Signal Processing Ltd.
- Enrollment
- 900
- Locations
- 3
- Primary Endpoint
- CAD status
- Last Updated
- 14 years ago
Overview
Brief Summary
This will be a registry study that will enroll patients referred for an ECG treadmill test with nuclear myocardial perfusion imaging (MPI). The high frequency QRS (HFQRS) information will be recorded and analyzed automatically and simultaneous with the standard ECG signals by the HyperQ System. Results of subsequent tests performed on each patient will be collected and used to enhance the reliability of designating each patient as a CAD-negative (i.e., no significant coronary artery disease) or a CAD-positive (i.e., significant coronary artery disease).
Investigators
Eligibility Criteria
Inclusion Criteria
- •18 years or older
- •Referred for exercise MPI due to suspected coronary artery disease
Exclusion Criteria
- •Acute Coronary Syndrome (Unstable angina/NSTEMI/STEMI)
- •Pre-excitation syndrome
- •QRS duration \> 120 ms
- •Atrial Fibrillation or significant ventricular arrhythmia
- •Treatment with Digoxin
- •Pacemaker with 100% pacemaker dependence
Outcomes
Primary Outcomes
CAD status
Time Frame: one month follow up
The main goal of this registry will be to compare sensitivity, specificity, positive and negative predictive values of the HyperQ HFQRS analysis for detecting the presence of coronary artery disease to that of standard ECG analysis.