To evaluate the effect of Probiotic on the amount of saliva collected and level of Secretory Immunoglobulin-A in completely edentulous patients
Phase 4
Completed
- Conditions
- Health Condition 1: Z00-Z99- Factors influencing health status and contact with health servicesHealth Condition 2: K06- Other disorders of gingiva and edentulous alveolar ridge
- Registration Number
- CTRI/2021/05/033807
- Lead Sponsor
- Dr Navdha Gupta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 52
Inclusion Criteria
Completely edentulous patients willing for conventional removable prosthesis.
Age criteria - Age group between 60 to 75 years.
Patients who are old denture wearers.
Patients who are not suffering from any chronic debilitating disease.
Absence of any kind of oral pathology.
Patients who understand and are willing to be a part of this study.
Exclusion Criteria
Patient suffering from Xerostomia.
Patients taking any kind of medication which affect salivary secretions from last three months like anti-histamnes, anti-cholinergics, anti-depressants, anti-emetics. anti-hypertensives, anti-pyschotics, diuretics.
Patients with any pyschosomatic disorder.
Presence of any malignancy of head and neck.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To find difference in the amount of saliva and levels of secretory IgA before and after the intake of Probiotics in completely edentulous patients.Timepoint: Multistrain probiotic is given to the patients to check their amount of saliva and level of secretory IgA in completely edentulous patients which is then compared with the control group not taking probiotic at baseline and then 3 months after complete denture insertion.
- Secondary Outcome Measures
Name Time Method To check changes in amounts of saliva and secretory IgA levels by intake of Probiotics before and after in treatment of completely edentulous patients.Timepoint: BAseline, 2 months, 3 months