The Effect of Myo-inositol on fertility rates in Poor ovarian Responder Women undergoing Assisted Reproductive technique
Phase 3
- Conditions
- Poor Ovarian Responder.Other primary ovarian failureE28.39
- Registration Number
- IRCT20180515039668N1
- Lead Sponsor
- Bandare-abbas University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
All women of reproductive age with reduced ovarian reserve (number of Antral follicles less than 7)
All women of reproductive age with decreased in anti-mullerian hormone to less than 1.2 ng/ml
All women of reproductive age over than 40 years
Having one of the above criteria is a prerequisite for entry into the study
Exclusion Criteria
Presence of endocrine and metabolic disorders such as polycystic ovary syndrome, hyperprolactinemia, diabetes and thyroid dysfunction
Pelvic pathology such as hydrosalpinx, uterine anomaly
Stages III to IV endometriosis and fibroma
Male factors infertility such as Oligo-Astheno-Teratozoospermia (OAT) or Azoospermia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oocyte Quility. Timepoint: 2-3 hr after oocyte collection. Method of measurement: Microscopic Evaluation.;Fertilization Rate. Timepoint: 24 hr after Injection. Method of measurement: Microscopic Evaluation.
- Secondary Outcome Measures
Name Time Method Biochemical Pregnancy Rate. Timepoint: 2 weeks after embryo transfer. Method of measurement: B-HCG evaluation.;Clinical pregnancy rate. Timepoint: 7 weeks after embryo transfer. Method of measurement: Sonography for fetal heart rate.