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Adherence in Upper Extremity Home-based Rehabilitation

Not Applicable
Completed
Conditions
Stroke
Interventions
Behavioral: Therapist guided training
Behavioral: Upper extremity (UE) Training
Registration Number
NCT05032638
Lead Sponsor
NYU Langone Health
Brief Summary

The objective of the proposal is to determine the feasibility of implementing Ecological Momentary Assessment (EMA) and Motivational Interviewing (MI) methods to enhance adherence for a 4-week self-initiated arm training protocol. A non-randomized feasibility study using a 4-week UE training protocol will be conducted in 15 individuals within the first 12 months post-stroke living in the community. EMA data will be collected using a mobile app to automate real-time collection of adherence data on a daily basis. MI will be used to produce self-generated training plans (training goals, training schedule), guided by the therapist before the start of training.

Detailed Description

Using a mixed methods design, the study will collect quantitative data before, during, and after training. Qualitative data will be collected after the training period and analyzed to explain the quantitative findings in depth, within the context of everyday life. Study aim 1 is to evaluate the feasibility of using EMA to measure adherence and of applying the MI approach. Quantitative data will include four indicators of adherence and accuracy. Interview responses will be used as qualitative data to elucidate participants' acceptance of the MI approach and feedback on using the EMA app. Study aim 2 is to explore to what extent UE outcomes change after the 4-week self-initiated home-based rehabilitation program. Outcomes will include UE use in real-world environments and self-perceived changes in UE use.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
15
Inclusion Criteria
  • Adults (> 18 years old) diagnosed with stroke at least 6 months ago at the time of screening
  • Living in the community
  • Have presence of UE motor impairment on the affected side (Fugl-Meyer Assessment scores < 66)
  • Availability of mobile technology (tablet or smartphone) with internet connection to use phone app and Zoom videochat)
  • Be medically stable
  • Able to provide written consent
Exclusion Criteria
  • Currently receiving active occupational or physical therapy for the treatment of the affected UE
  • Presence of severe cognitive impairment (Mini Mental Status Exam <24)
  • Self-reported moderate to severe pain of the affected UE with use
  • Presence of unilateral spatial neglect (Star Cancellation Task scores < 44)
  • Presence of neurological diagnosis other than stroke.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Experimental GroupTherapist guided trainingSubjects with motor impairment will work closely with an occupational therapist to identify a goal and select activities that they will work on at home to improve the function of their affected arm.
Experimental GroupUpper extremity (UE) TrainingSubjects with motor impairment will work closely with an occupational therapist to identify a goal and select activities that they will work on at home to improve the function of their affected arm.
Primary Outcome Measures
NameTimeMethod
Rates of adherence at individual and group level measured through frequencyDay 39 visit

Frequency will be calculated by dividing the number of sessions completed by the total number of sessions available for 4-week period

Rates of adherence at individual and group level measured through intensityDay 39 visit

Intensity data will be collected using a 3-point ordinal ratings scale to determine perceived intensity of practice for each session (mild- moderate- intense).

Rates of adherence at individual and group level measured through durationDay 39 visit

Duration data will be collected using open end responses to report total number of minutes of UE training completed that day

Decision making factors effecting the program adherence through semi-structured interviewsDay 39 visit

Semi-structured interviews will be conducted with all participants to collect qualitative data on participants' experiences related to the shared decision-making process in phase 1, and adherence to arm training in phase 2 of study.

Secondary Outcome Measures
NameTimeMethod
Change scores in Motor Activity Log from baseline to discharge and baseline to follow-upDay 4 visit, Day 37-39 visit, Day 65-67 visit

Motor Activity Log (MAL) is a valid and reliable self-report questionnaire for individuals in the subacute and chronic phase after stroke. Originally created as the primary outcome for Constraint Induced Movement Therapy, the MAL captures spontaneous use of the affected UE in daily life. It consists of 28 items reflecting basic and instrumental activities of daily living items. Scoring is based on an ordinal scale ranging from 1-5, and final scores are determined by calculating the mean of all item scores. This study will use the amount of use subscale for this study.

Change scores in Fugl-Meyer Assessment from baseline to discharge and baseline to follow-upDay 4 visit, Day 37-39 visit, Day 65-67 visit

FMA is a valid and reliable UE assessment to measure motor impairment in stroke. It consists of 33 items reflecting typical shoulder and hand motions in and out of synergy patterns characteristic of motor recovery after stroke. It is the gold standard performance-based assessment in UE stroke rehabilitation with an established minimal clinically important difference (MCID) of 4.25-7.25 points for chronic stroke patients.

Change scores in UE accelerometry data calculated using bilateral magnitude ratio from baseline to discharge and baseline to follow-up.Day 4 visit, Day 37-39 visit, Day 65-67 visit

Wrist worn accelerometers can be used to provide objective, valid, and reliable data on general UE motion in home settings. As a secondary outcome for adherence, we will collect bilateral UE accelerometry data continuously for 24 hours at all timepoints to determine if there are any changes in UE motion of the affected side in relation to the unaffected side before and after the intervention. Commercially available Actigraph GT9X Link wrist sensors will be used to collect bilateral UE motion at baseline, discharge, and follow up.

Change scores in Canadian Occupational Performance Measure from baseline to discharge and baseline to follow-upDay 4 visit, Day 37-39 visit, Day 65-67 visit

The Canadian Occupational Performance Measure (COPM) is a valid and reliable individualized self-report measure that quantifies a participants' perception of everyday performance. Participants rate their change in their performance and satisfaction on a scale of 1 (unable to perform/not satisfied) to 10 (able to perform, extremely satisfied). A change of two or more points is considered clinically significant.

Trial Locations

Locations (1)

NYU Langone Health

🇺🇸

New York, New York, United States

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