ISRCTN34471493已完成未知
Control of periodontal inflammation, systemic inflammatory responses and cognitive decline: a comparative study of standard oral care versus periodontal care
King's College London (UK)0 个研究点目标入组 60 人开始时间: 2013年8月16日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Adults aged 70 years or older, either sex
- •2. Amnestic according to Consortium to Establish a Registry for Alzheimer's Disease (CERAD) cognitive battery norms
- •3. Mini?Mental State Examination (MMSE) score range between 24-30
- •4. Geriatric Depression Scale less than/equals 4/5
- •5. Clinical Dementia rating scale score of less than/equals 0.5
- •6. Participants should be nonsmoking, in good general health and English speaking in order to allow valid cognitive assessment to take place
- •7. Willing and able to participate in study
排除标准
- •1. Less than 70 years old
- •2. Recent change in relevant medication
- •3. Current or recent smoker.
- •4. With 8 teeth or less
- •5. Not deemed sufficiently fit to undergo operative dental treatment including extractions
- •6. Recent active periodontal treatment
- •7. Reporting a history of local oropharyngeal radiotherapy resulting in oral dryness
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