Clinical study on the effect of knee joint bone mineral density on the treatment of knee osteoarthritis with kidney tonifying herbs
- Conditions
- Knee osteoarthritis
- Registration Number
- ITMCTR2100004401
- Lead Sponsor
- Baoshan District Hospital of integrated traditional Chinese and Western Medicine (Baoshan hospital)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
The diagnostic criteria of OA in knee osteoarthritis:
1. Repeated knee pain in the past month;
2. X-ray films (standing or weight-bearing position) showed narrowing of joint space, subchondral osteosclerosis and / or cystic change, and osteophyte formation at the joint margin;
3. Aged >= 50 years;
4. Morning stiffness <= 30 minutes;
5. There is bone rub fricative sound (feeling) when moving.
General criteria:
1. Aged >= 50 years old;
2. Gender: male and female randomly;
3. Duration of knee osteoarthritis: 1-12 months.
X-ray grading standard of knee arthritis: Kellgren Lawrence grade II, III. Pain degree standard: VAS pain score 4-7.
1. Completed with bone tumor, rheumatoid, tuberculosis, suppuration and intra-articular fracture in acute stage;
2. Patients with congenital deformity of knee joint;
3. Patients with pedestrian knee arthroplasty;
4. Patients with severe coronary heart disease, hypertension, tumor, stroke, dementia and other diseases and various Senile Osteoarthritis, which affect the judgment;
5. Secondary osteoporosis caused by drugs or other diseases (such as hyperthyroidism, nephritis, diabetes, suppurative myelitis, etc.); psychotic patients and uncooperative persons.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method WOMAC scale for knee joint function;
- Secondary Outcome Measures
Name Time Method VAS pain score;