The Impact of Anti- Asthmatic Medications on Salivary pH and Dental Caries Pattern in a Group of Egyptian Children With Bronchial Asthma

• Conditions: pH
• Interventions: Drug: Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)

• Registration Number: NCT03877874
• Lead Sponsor: Cairo University

Brief Summary

The impact of Anti- Asthmatic medications on salivary pH and dental caries pattern in a Group of Egyptian Children with Bronchial Asthma.

Detailed Description

Due to lack of published studies about the impact of anti-asthmatic medications on salivary pH and dental caries pattern among the Egyptian children diagnosed with Bronchial Asthma, this study will be conducted to cover this point.

Study Timeline

• Study First Submitted: 2019-03-12
• Study First Submitted QC: 2019-03-13
• Study First Posted: 2019-03-18
• Status Verified: 2021-01
• Last Update Submitted: 2021-01-28
• Last Update Posted: 2021-02-01
• Study Start: 2021-07
• Primary Completion: 2021-09
• Study Completion: 2021-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• • Children aged 6-12 years old diagnosed with Bronchial asthma (Mixed dentition stage).
• Control group : a matched group aged 6-12 years old
• Patients taking regular medications for the treatment of Bronchial asthma at least for 1 year back
• Both male and female patients will be included.

Exclusion Criteria

• No other systemic Diseases.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Asthmatic children	Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)	* Aironyl syrup(Terbutaline sulfate ................. 1.5mg) 0.075-0.29 mg/ kg body weight 3 times daily * Apidone syrup(Dexamethone) (0.02 to 0.3 mg per kilogram (kg) of body weight per day, divided and taken 3 or 4 times a day).

Primary Outcome Measures

Name	Time	Method
pH of Saliva	1year	Digital pH electrode meter

Secondary Outcome Measures

Name	Time	Method
pattern of Dental caries	1year	DMFs/defs index