Effects of Transcranial Direct Current Stimulation (tDCS) on Gestural-verbal Brain Associations: the Role of Cognitive Embodiment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- response time in semantic decision task
研究概览
简要总结
The main objective of the proposed research is to extend our understanding of how gesture and language interact, focusing on the role of cognitive embodiment in this interaction, and to explore the neural systems that support links between language and actions systems.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Right handedness
- •unobtrusive neuropsychological screening
排除标准
- •History of severe alcoholism or use of drugs.
- •Severe psychiatric disorders such as depression, psychosis (if not in remission) and severe untreated medical problems.
- •Contraindication for MRT (claustrophobia, metallic implants, ferromagnetic metals in the body, disorders of thermoregulation, pregnant women).
结局指标
主要结局
response time in semantic decision task
时间窗: assessed during stimulation or sham stimulation of semantic decision task (last approximately 10 min) at specific timepoint within 2 weeks
Comparing response time in semantic decision task under anodal tDCS compared to sham stimulation (change from sham stimulation)
performance in attentional load task
时间窗: assessed during stimulation or sham stimulation of attentional load task (last approximately 6 min) at specific timepoint within 2 weeks
Attentional load task: Participants are presented with a 6 positions ring that includes different shapes, they have to press V when they see a square and N when they see a diamond. They will have to ignore any shapes other than square and diamond within the ring or distractors that appear outside the ring. Comparing performance in attentional load task under anodal tDCS compared to sham stimulation (change from sham stimulation)
performance in motor task
时间窗: assessed during stimulation or sham stimulation of motor task (last approximately 4 min) at specific timepoint within 2 weeks
Motor Task: Participants are presented with a red Box and they have to click a button each time they see it as fast as they can. Comparing performance in motor task under anodal tDCS compared to sham stimulation (change from sham stimulation)
次要结局
- Functional connectivity predictors(assessed during baseline testing)
- Other cognitive outcomes: change in Attention performance(change in attention performance from baseline after 30 min (approximately))
- Other cognitive outcomes: change in working memory performance(change in working memory performance from baseline after 30 min (approximately))
研究者
Agnes Flöel
Prof.Dr.med.
Charite University, Berlin, Germany