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Home Based Electrical Stimulation on Post-stroke Lower Limb Tightness.

Not Applicable
Conditions
Spasticity as Sequela of Stroke
Interventions
Other: Feasibility and Impact of Home-based Electrical Stimulation Program
Registration Number
NCT04932668
Lead Sponsor
University of Malaya
Brief Summary

Spasticity is a common complication post stroke. Post-stroke spasticity along with weakness and lack of coordination result in gait abnormalities and functional limitations. Recent treatment option include neuromuscular electric stimulation (NMES), a form of therapy that applies electrical currents to produce contraction of innervated muscle by depolarizing local motor nerves. Currently, there are wide varieties of NMES devices available commercially for consumer.

The main purpose of this study is to evaluate the feasibility and acceptability of a home-based NMES program on lower limb spasticity in patient with post-stroke more than 6 months and to assess the impact of the program. This is single arm prospective intervention study. Patient will apply home-based NMES on their leg for 20 minutes, 5 days a week for 4 weeks. At the end of the study, an outcome measures will be assessed and patient will be required to answer a questionnaires on their experience.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
20
Inclusion Criteria
  1. Post stroke (hemorrhagic or ischemic) with ankle plantarflexor (gastrocnemius and soleus) spasticity MAS 1+ to MAS 3,
  2. Post stroke more than 6 months,
  3. At least 18 years old,
  4. Able to ambulate 10 meter either independently or aided (single point stick or quadripod)
  5. Compliant to outpatient therapy.
  6. Minimal cognitive (MMSE> 24) and minimal sensory impairment,
  7. Stable neurological and medical condition
Exclusion Criteria
  1. Introduction or changes in anti-spastic medication dose within 3 months or during study period,
  2. Receiving intervention for spasticity (eg BoNT or serial casting) within 3 months or during research period,
  3. New neurological condition/disease,
  4. Presence of contraindications to NMES, which is: Pregnancy, Malignancy, Presence of electronic implant eg cardiac pacemaker, cardioverter defibrillator, Uncontrolled seizure/epilepsy, Infected tissues/ tuberculosis or osteomyelitis, Impaired lower limb circulation/ DVT/ thrombophlebitis, Recent fracture or osteoporosis, Actively bleeding tissue or person with untreated hemorrhagic disorder, Damaged or skin diseases at the affected lower limb

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Home-based Electrical Stimulation Program for lower limb spasticityFeasibility and Impact of Home-based Electrical Stimulation ProgramSingle arm prospective intervention study to assess the feasibility and impact of a home-based program. Patient will apply home-based NMES on their leg for 20 minutes, 5 days a week for 4 weeks. At the end of the study, an outcome measures will be assessed and patient will be required to answer a questionnaires on their experience.
Primary Outcome Measures
NameTimeMethod
Retention Rate4 weeks

The proportion of patients who completed the program. Patient completed divided with patient recruited, expressed in percentage (%).

Acceptability4 weeks

Acceptability as evaluated at the end of the intervention by brief structured questionnaire developed for this study using 5 point Likert scale with 1 (strongly agree) and 5 (strongly agree).

Secondary Outcome Measures
NameTimeMethod
Clinical measurement of spasticity4 weeks (pre and post assessment)

Modified Tardieu Scale (R1 and R2 angle of ankle dorsiflexion)

Ankle dorsiflexion muscle strength4 weeks (pre and post assessment)

Manual Muscle Testing as measured in 0-5 (with 0 no movement and 5 is the strongest)

Functional Outcome4 weeks (pre and post assessment)

10 meter walking test

Trial Locations

Locations (1)

University Malaya Medical Center

🇲🇾

Kuala Lumpur, Malaysia

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