Characterization of Suicidal Depression

Completed

• Conditions: Depression

• Registration Number: NCT05046587
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Antidepressants are widely used to prevent suicidal risk. However, even though the use of antidepressants has been associated with a 40-60% decrease in suicidal risk, they do not seem to be sufficient and appropriate. Indeed recent studies have shown that patients with a history of suicide attempt and/or with current suicidal ideation (SI) respond less well to antidepressant treatments. This suggests that patients with depression with SI may be different from those with depression without SI, thus requiring specific treatments for both SI reduction and depressive remission. In other words, suicidal depression may be a specific subtype of depression.

The study aims to characterize the clinical phenotype of patients with suicidal depression vs. those without suicidal depression, and to assess the occurrence of suicidal events at one year in patients with suicidal depression vs. without suicidal depression.

All data having already been collected during the particpation of patients in various clinical research studies of the department

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-01
• Study First Submitted: 2021-07-05
• Primary Completion: 2021-09-01
• Study First Submitted QC: 2021-09-14
• Study First Posted: 2021-09-16
• Study Completion: 2021-09-30
• Status Verified: 2021-11
• Last Update Submitted: 2021-11-12
• Last Update Posted: 2021-11-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 898

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
characterization of the patient clinical phenotype	day 1	characterization of the patient clinical phenotype

Secondary Outcome Measures

Name	Time	Method
Suicidal events at one year	1 year	Occurrence of suicidal events (actual, interrupted and aborted or self-aborted suicide attempts) based on the patient medical records
Hospitalization for suicidal ideation	1 year	Occurrence of hospitalization for suicidal ideation, based on the patient medical record

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France