Mycophenolate mofetil in Antiretroviral Naive patients 2 (MAN2 study)

Academic Medical Centre (AMC) (Netherlands)0 个研究点目标入组 90 人开始时间: 2006年1月27日最近更新: 2019年2月11日

试验速览

暂无简介。

•1. Patient is =18 years of age
•2. Patient has a proven HIV-1 infection (with antibodies against HIV-1 and a detectable plasma HIV-1 RNA measured for the first time at least 6 months prior to inclusion)
•3. Patient is HIV-1 treatment naive
•4. CD4+ T lymphocyte count >250 and =450 x 10^6/l
•5. No signs or history of AIDS defining events
•6. No use of other medications that might possibly influence the effects of MMF
•7. Male or female sex and willingness to practice effective contraception during the study

•1. Plasma HIV-1 RNA <10,000 copies/ml
•2. Autoimmune disease
•3. Active hepatitis B or C virus infection
•4. Other chronic diseases
•5. Recent infectious disease other than HIV-1
•6. Treatment with immunomodulatory or anti-inflammatory medication in the past 6 months
•7. For female patients: pregnancy and lactation
•8. Any other condition, illness or use of medication which according to the investigator is not compatible with the use of the study medication or which could interfere with the evaluations required by the study

发起方

Academic Medical Centre (AMC) (Netherlands)