Effect of Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis

Not Applicable

• Conditions: Knee Osteoarthritis; Cartilage Injury
• Interventions: Device: shock wave device

• Registration Number: NCT03962270
• Lead Sponsor: Peking University Third Hospital

Brief Summary

In this study, the effectiveness of ESWT in the treatment of knee OA was investigated from the perspective of cartilage injury，and to prove that shockwave could delay the early and middle stage OA progression by improving cartilage condition

Detailed Description

Not available

Study Timeline

• Study Start: 2018-08-01
• Study First Submitted: 2018-10-30
• Status Verified: 2019-05
• Study First Submitted QC: 2019-05-23
• Last Update Submitted: 2019-05-23
• Study First Posted: 2019-05-24
• Last Update Posted: 2019-05-24
• Primary Completion: 2019-08-01
• Study Completion: 2019-08-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Knee joint ROM normal or near normal: flexion 110 ° or reach 0 ° or less
• MR prompt exist cartilage damage, there is no lack of full-thickness cartilage
• Kellgren - Lawrence (K - L) grade II - III grade
• The international association of cartilage repair cartilage damage grading system (ICRS) class I - III
• Informed consent and sign relevant documents
• Follow doctor's instructions and follow up on time

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Exclusion Criteria

• Metabolic arthritis
• Trauma of bone joint
• Inflammatory diseases
• Previous knee surgery history
• History of knee cavity injection in the past 6 months
• Serious cardiovascular diseases, pulmonary diseases or other serious diseases affecting survival, etc

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group	shock wave device	-
Treatment group	shock wave device	-

Primary Outcome Measures

Name	Time	Method
magnetic resonance imaging of knee	Three months after treatment	t2 mapping

Trial Locations

Locations (1)

Peking Univercity Third Hospital; 🇨🇳 Beijing, No State Or Province, China