Impact of Arterial Cannulation Site on Vasopressor Requirement in Cardiac Surgery

• Conditions: Cardiac Disease
• Interventions: Device: Choice of arterial cannulation site at the beginning of the surgery

• Registration Number: NCT04620694
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Choice of arterial cannulation site during cardiac surgery is controversial. Some physicians in our institution prefer radial artery site, others prefer aortic site (via femoral artery or brachial artery). The investigators aim to compare these two strategies for vasopressor requirement. The study hypothesis is that radial artery cannulation is associated with a larger dose of vasopressor due aortic to radial arterial pressure gradient phenomenon.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-01
• Status Verified: 2020-11
• Study First Submitted: 2020-11-03
• Study First Submitted QC: 2020-11-06
• Last Update Submitted: 2020-11-06
• Study First Posted: 2020-11-09
• Last Update Posted: 2020-11-09
• Primary Completion: 2021-02
• Study Completion: 2021-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 350

Inclusion Criteria

• Adult patient
• Scheduled for cardiac surgery with cardiopulmonary bypass

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Exclusion Criteria

• More than one arterial cannula at the beginning of the surgery

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Aortic cannulation (brachial or femoral artery)	Choice of arterial cannulation site at the beginning of the surgery	Patients whom femoral or brachial artery was cannulated at the beginning of the surgery. Active comparator

Primary Outcome Measures

Name	Time	Method
Intraoperative vasopressor requirement	end of surgery	Mean intraoperative dosage of Norepinephrine (µg.kg-1.min-1)

Trial Locations

Locations (1)

Hôpital Louis Pradel; 🇫🇷 Lyon, France