Cross Linking for Treatment of Corneal Infection
Not Applicable
Terminated
- Conditions
- Infectious Keratitis
- Interventions
- Device: UVX Light
- Registration Number
- NCT00912509
- Lead Sponsor
- Price Vision Group
- Brief Summary
This study is comparing 45 minute and 30 minute treatment durations with the UVX corneal cross linking system to treat corneal infections.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- diagnosis of infectious keratitis
Exclusion Criteria
- corneal ulcer that has perforated
- corneal ulcer that has produced a descemetocele
- women who are pregnant or breastfeeding
- patients who are immunocompromised or unwilling or unable to comply with a medication regimen
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 30 minute light duration riboflavin 30 minute treatment with UVX light 30 minute light duration UVX Light 30 minute treatment with UVX light 45 minute light duration UVX Light 45 minute treatment with UVX light
- Primary Outcome Measures
Name Time Method Time to Re-epithelialization Day 1, day 2, day 3, day 4, day 5, day 6, day 7, week 2, and subsequent weekly assessments until re-epithelialization is complete
- Secondary Outcome Measures
Name Time Method Time to Resolution of Stromal Infiltration day 1, day 2, day 3, day 4, day 5, day 6, day 7, week 2, and subsequent weekly assessments until infiltrate is completely resolved
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie riboflavin-mediated corneal cross-linking in infectious keratitis treatment?
How does the UVX cross-linking system compare to standard-of-care treatments for bacterial and fungal keratitis?
Are there specific corneal biomarkers that predict treatment response to UVX cross-linking in infectious keratitis?
What are the potential adverse events associated with UVX corneal cross-linking and how are they managed?
What combination therapies or alternative cross-linking systems are being explored for infectious keratitis treatment?
Trial Locations
- Locations (1)
Price Vision Group
🇺🇸Indianapolis, Indiana, United States
Price Vision Group🇺🇸Indianapolis, Indiana, United States