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Cross Linking for Treatment of Corneal Infection

Not Applicable
Terminated
Conditions
Infectious Keratitis
Interventions
Device: UVX Light
Registration Number
NCT00912509
Lead Sponsor
Price Vision Group
Brief Summary

This study is comparing 45 minute and 30 minute treatment durations with the UVX corneal cross linking system to treat corneal infections.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • diagnosis of infectious keratitis
Exclusion Criteria
  • corneal ulcer that has perforated
  • corneal ulcer that has produced a descemetocele
  • women who are pregnant or breastfeeding
  • patients who are immunocompromised or unwilling or unable to comply with a medication regimen

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
30 minute light durationriboflavin30 minute treatment with UVX light
30 minute light durationUVX Light30 minute treatment with UVX light
45 minute light durationUVX Light45 minute treatment with UVX light
Primary Outcome Measures
NameTimeMethod
Time to Re-epithelializationDay 1, day 2, day 3, day 4, day 5, day 6, day 7, week 2, and subsequent weekly assessments until re-epithelialization is complete
Secondary Outcome Measures
NameTimeMethod
Time to Resolution of Stromal Infiltrationday 1, day 2, day 3, day 4, day 5, day 6, day 7, week 2, and subsequent weekly assessments until infiltrate is completely resolved

Trial Locations

Locations (1)

Price Vision Group

🇺🇸

Indianapolis, Indiana, United States

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