Effect of Bronchodilatator Testing on Multiple-breath-washout (MBW) Derived Lung Function Parameters

Completed

• Conditions: Obstructive Ventilation Disorders
• Interventions: Device: multiple-breath-washout test; Drug: Bronchodilator Agents

• Registration Number: NCT02826226
• Lead Sponsor: Universitätsmedizin Mannheim

Brief Summary

The investigators aim to evaluate the effect of bronchodilatator testing on multiple-breath-washout derived lung function parameters.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-05
• Study First Submitted: 2016-06-30
• Study First Submitted QC: 2016-07-05
• Study First Posted: 2016-07-07
• Status Verified: 2018-12
• Primary Completion: 2018-12
• Study Completion: 2018-12
• Last Update Submitted: 2018-12-30
• Last Update Posted: 2019-01-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 145

Inclusion Criteria

• known or suspected obstructive ventilation disorder
• clinical indication for bronchodilator testing

Exclusion Criteria

• pregnancy
• inability to participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
obstructive ventilation disorder	multiple-breath-washout test	patients with known or suspected obstructive ventilation disorder and clinical indication for bronchodilator testing
obstructive ventilation disorder	Bronchodilator Agents	patients with known or suspected obstructive ventilation disorder and clinical indication for bronchodilator testing

Primary Outcome Measures

Name	Time	Method
change of lung clearance index (LCI) as determined by multiple breath washout	60 minutes

Secondary Outcome Measures

Name	Time	Method
repeatability of lung clearance index (LCI)	60 minutes

Trial Locations

Locations (1)

Universitätsmedizin Mannheim; 🇩🇪 Mannheim, Germany