A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser
Not Applicable
Completed
- Conditions
- HyperopiaAstigmatismMyopia
- Interventions
- Procedure: LASIK and PRK
- Registration Number
- NCT01135719
- Lead Sponsor
- Edward E. Manche
- Brief Summary
Subjects with myopia, hyperopia and astigmatism are being randomized to be treated in one eye with a wavefront-guided excimer laser and their fellow eye treated with a wavefront-optimized excimer laser.
- Detailed Description
Subjects with myopia, hyperopia and astigmatism are being randomized by ocular dominance to be treated with either PRK or LASIK. One eye will be treated with a wavefront-guided excimer laser and the fellow eye will be treated with a wavefront optimized excimer laser.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 137
Inclusion Criteria
- Healthy subjects age 21 and older.
- Subjects with nearsightedness, farsightedness and/or astigmatism.
Exclusion Criteria
Autoimmune diseases.
- Children.
- Women pregnant or nursing.
- Ectatic corneal disease.
- Previous ocular surgery.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Wavefront guided LASIK/PRK LASIK and PRK Wavefront-guided LASIK/PRK Wavefront optimized LASIK/PRK LASIK and PRK Wavefornt optimized LASIK/PRK
- Primary Outcome Measures
Name Time Method Changes in 25 and 5% low contrast visual acuity. One year Improvement in uncorrected visual acuity One year Changes in best spectacle corrected visual acuity. One year
- Secondary Outcome Measures
Name Time Method Changes in higher order aberrations. One year Topographic changes. One year Quality of vision changes. One year
Trial Locations
- Locations (1)
Stanford University School of Medicine
🇺🇸Stanford, California, United States