Efficacy of Pulsed High Intensity Laser Therapy in Psoriatic Hand Arthritis

Not Applicable

Completed

• Conditions: High Intensity Laser Therapy; Psoriasis; Hand

• Registration Number: NCT06665282
• Lead Sponsor: Cairo University

Brief Summary

The purpose of the study was to evaluate the therapeutic efficacy of pulsed high intensity level laser therapy in improving symptoms of psoriatic hand arthritis.

Detailed Description

Psoriatic arthritis is a chronic, inflammatory joint disease affecting 20%-30% of patients with psoriasis. It affects peripheral joints and axial skeleton, causing pain, stiffness, swelling, and joint destruction. High-intensity laser therapy can control inflammation and improve pain relief, range of motion, and functional improvement. This study aims to examine High-intensity laser therapy efficacy in managing Psoriatic arthritis, aiming to provide a safe, effective, and noninvasive treatment method.

Study Timeline

• Study Start: 2023-08-01
• Primary Completion: 2024-05-01
• Study Completion: 2024-07-01
• Status Verified: 2024-10
• Study First Submitted: 2024-10-29
• Study First Submitted QC: 2024-10-29
• Last Update Submitted: 2024-10-29
• Study First Posted: 2024-10-30
• Last Update Posted: 2024-10-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

• Both sexes of patients their age range between 30-50 years.
• Bilateral PsA following psoriasis
• All participants who are diagnosed with PsA, and experience clinical symptoms such as pain, swelling, tenderness and stiffness less than 1 year from the beginning of disease.
• All patients enrolled to the study will have their informed consent.

Exclusion Criteria

• Positive rheumatic factor
• Circulatory disorders
• Diabetes
• Pregnant woman
• Skin diseases like urticaria.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Assessment of change of Hand Grip Strength using manual dynamometer	at baseline and after 2 months	The Handheld Jamar dynamometer device 12-0600 will be used to measure hand grip strength, with a readout in pounds and kilograms. The strength will be measured with the elbow at 90° according to the American Society of Hand Therapists' recommendations. Patients will be instructed to sit while the affected limb is placed in shoulder adduction, internal rotation, elbow flexion, forearm mid position, and wrist neutral position. Three consecutive measurements will be performed with a 2-minute interval, and the mean strength value of the three trials will be considered as the hand grip measure.

Secondary Outcome Measures

Name	Time	Method
assessment of Joint counts for tenderness	at baseline and after 2 months	Joint counts for tenderness was the sum of the number of the affected joints
assessment of Joint swelling count	at baseline and after 2 months	Joint swelling count is the sum of the swollen joints at the dominant hand before and after the treatment
assessment of pain intensity using visual analogue scale	at baseline and after 2 months	The Visual Analog Scale was used to measure pain intensity, with a 100mm horizontal line starting with no pain and ending with worse pain. Patients marked their pain intensity points on the scale, and the researcher measured the distance between the "no pain" mark and the patient's mark, providing a range of scores from 0 to 100mm.

Trial Locations

Locations (1)

out-patient clinic, faculty of physical therapy, Cairo university; 🇪🇬 Giza, Egypt