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Pancreatic intra-operative NOdal status: should it influence DEcision making during pancreatoduodenectomy in patients with pancreatic or periampullary cancer?

Completed
Conditions
Pancreatic or periampullary malignancy
Registration Number
NL-OMON28118
Lead Sponsor
Amsterdam UMC
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
700
Inclusion Criteria

Adult patients (> 18 yrs)
- Pancreatoduodenectomy (either classic Whipple or pylorus preserving) for suspected pancreatic or periampullary malignancy

Exclusion Criteria

- Other active malignancy or previous history of any malignancy if not treated with curative intent >5 years previously
- Pregnancy

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Investigate the effect of lymph node metastases in stations 8a, 9 and 16b1 on overall survival in patients undergoing (classical Whipple or pylorus preserving) pancreatoduodenectomy for pancreatic or peri-ampullary cancer.
Secondary Outcome Measures
NameTimeMethod
To determine:<br>1. The prevalence of lymph node metastases in stations 8a, 9 and 16b1 in histopathologically proven pancreatic or peri-ampullary cancer.<br>2. In-hospital mortality / conditional survival
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