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Effect of pentoxifylline in preventing contrast-induced nephropathy

Phase 2
Conditions
ST elevation myocardial infarction.
Acute myocardial infarction
Registration Number
IRCT2014092819316N1
Lead Sponsor
Vice chancellor for research of Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
182
Inclusion Criteria

Consent to participate; ST elevation myocardial infarction (STMI) and age over 18 years. Exclusion criteria: serum creatinine more than 1.5 mg/dl, heart failure; history of end-stage renal failure or being on dialysis; use of N-acetyl cysteine, theophylline, aminoglycosides, and nonsteroidal anti-inflammatory drugs; intravenous contrast media administration within the past two days; pulmonary edema; multiple myeloma; and uncontrolled hypertension

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Serum creatinine levels. Timepoint: Before angioplasty, two days after angioplasty. Method of measurement: Blood test.;Contrast-induced nephropathy. Timepoint: 48 hours after angioplasty. Method of measurement: Blood test.
Secondary Outcome Measures
NameTimeMethod
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