Survival and Quality of Life After Liver Transplantation in Patients Aged 65 and Over
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 125
- 试验地点
- 1
- 主要终点
- Assessment of survival and quality of life after liver transplantation according to the quality of life score
研究概览
简要总结
The main objective of this non-interventional, single-center study is to assess survival and associated factors at 1 year in patients aged 65 and over who received liver transplantation
详细描述
The expected benefits of this study are to identify the preoperative risk factors of mortality from liver transplant failure in patients aged 65 and over (90-day mortality and 1 and 3-year survival) will allow better selection. candidates for this age group. In the current context of organ shortage, this study should make it possible to reduce the number of risky transplants and thus improve the allocation of grafts.Inclusion of patients who meet the inclusion criteria will be carried out during their hospitalization in the surgical department of the hepato-bilary center.
Included patients will receive a standardized geriatric assessment in addition to the usual assessment for a liver transplant.
The geriatric assessment will be carried out and conducted as follows: geriatric scores and quality of life questionnaires. Two geriatricians will perform the physical examination and blindly estimate each other's probability of survival at 90 days using a Likert scale.
Geriatricians will be blinded to hepatic data (reasons for transplantation). The consultation as well as the completion of the questionnaire will be carried out during the pre-transplantation assessment.
Survival and quality of life will be assessed at 3 and 12 months post-transplantaion.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Candidates for liver transplantation
- •Having expressed non-oppostion to his participation in study and documented in his medical file
- •With social coverage
排除标准
- •Emergency transplant patients
- •Patient already included in another study
- •Patient under guardianship or curatorship
- •Expressing his opposition to participate in the study
结局指标
主要结局
Assessment of survival and quality of life after liver transplantation according to the quality of life score
时间窗: 12 Months
次要结局
- Detecting depression in the elderly according the Geriatric Depression Scale (GDS)(12 Months)