A Clinical Study of the Effects of Environmental Pollution on Obesity

Active, not recruiting

• Conditions: Obesity and Overweight

• Registration Number: NCT06670703
• Lead Sponsor: Dong Peng

Brief Summary

This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which environmental pollution promotes obesity.

Detailed Description

Firstly, the effects of environmental pollution on obese patients were investigated by analysing the baseline conditions and obesity levels (including BMI, waist circumference, hip circumference, etc.) and underlying diseases of obese patients in regions with different pollution levels. Secondly, the association between environmental pollution levels on blood test characteristics (including renal function, sex hormones, glucose tolerance test, trace elements, liver function and blood routine) of obese patients was investigated to find possible mechanisms.

Study Timeline

• Study Start: 2011-01-01
• Status Verified: 2024-10
• Primary Completion: 2024-10-30
• Study Completion: 2024-10-30
• Study First Submitted: 2024-10-31
• Study First Submitted QC: 2024-10-31
• Last Update Submitted: 2024-10-31
• Study First Posted: 2024-11-01
• Last Update Posted: 2024-11-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

• Age ≥18 years;
• obese patients with BMI ≥30;
• patients without surgical treatment prior to enrolment;
• willingness to participate in the study and sign an informed consent form;
• complete clinical data.

Exclusion Criteria

• patients with systemic diseases such as severe cardiorespiratory insufficiency affecting the choice of treatment regimen;
• patients assessed by the investigator to be inappropriate for enrolment;
• patients with incomplete clinical data.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence of obesity	From 18 years old until the developing obesity, through study completion, an average of 5 year.	the time for overweight to obesity

Trial Locations

Locations (3)

The First Affiliated Hospital of Chongqing Medical University; 🇨🇳 Chongqing, Chongqing, China

Affiliated Hospital of Yunnan University; 🇨🇳 Kunming, Yunnan, China

The Second People's Hospital of Qujing; 🇨🇳 Kunming, Yunnan, China