A Clinical Study of the Effects of Environmental Pollution on Obesity
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity and Overweight
- Sponsor
- Dong Peng
- Enrollment
- 800
- Locations
- 3
- Primary Endpoint
- incidence of obesity
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which environmental pollution promotes obesity.
Detailed Description
Firstly, the effects of environmental pollution on obese patients were investigated by analysing the baseline conditions and obesity levels (including BMI, waist circumference, hip circumference, etc.) and underlying diseases of obese patients in regions with different pollution levels. Secondly, the association between environmental pollution levels on blood test characteristics (including renal function, sex hormones, glucose tolerance test, trace elements, liver function and blood routine) of obese patients was investigated to find possible mechanisms.
Investigators
Dong Peng
Principal Investigator
First Affiliated Hospital of Chongqing Medical University
Eligibility Criteria
Inclusion Criteria
- •Age ≥18 years;
- •obese patients with BMI ≥30;
- •patients without surgical treatment prior to enrolment;
- •willingness to participate in the study and sign an informed consent form;
- •complete clinical data.
Exclusion Criteria
- •patients with systemic diseases such as severe cardiorespiratory insufficiency affecting the choice of treatment regimen;
- •patients assessed by the investigator to be inappropriate for enrolment;
- •patients with incomplete clinical data.
Outcomes
Primary Outcomes
incidence of obesity
Time Frame: From 18 years old until the developing obesity, through study completion, an average of 5 year.
the time for overweight to obesity