A Clinical trial comparing corneal morphological (changes in structure, thickness) and biomechanical (corneal strength changes) Outcomes of Femtosecond laser assisted LASIK refractive surgery with two machines namely Visumax -MEL90 and Wavelight FS200-EX500 Lasers
Not Applicable
- Conditions
- Health Condition 1: H521- Myopia
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Patients undergoing FS-LASIK for myopia or myopic astigmatism
2)Stable refractive error for >1 year
3)Minimum calculated RSBT- 300 microns
4)Patients willing to give informed consent
5)Patients willing for follow up
Exclusion Criteria
1)Progressive or unstable myopia
2)External ocular disease/ keratoconus (including forme-fruste)/ Pellucid marginal degeneration.
3)Diabetes, connective tissue disease, Atopy; pregnant or nursing patients.
4)Corticosteriods or antimetabolites use
5)Previous corneal surgery/ Re-treatment, not willing to follow up.
6)Soft contact lens use in past 2 weeks or rigid gas permeable contact lens wear in past 4 weeks.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Central Flap ThicknessTimepoint: Day 1, 1 week, 1 month, 3 months
- Secondary Outcome Measures
Name Time Method 1)Corneal Biomechanical outcomes (Including DA, A length, A velocity, CBI-LVC index) <br/ ><br>2)Anterior chamber angle parameters (ACD, ARA, TIA, TISA, AOD) <br/ ><br>3)Posterior Segment Changes (Bursa premacularis, Area of Martigiani, RNFL thickness , GCL thickness, CMT) <br/ ><br>4)Flap shape, regularity, accuracy <br/ ><br>5)Visual Quality (HOAs, Strehl Ratio, MTF, PSF) <br/ ><br>6)Suction timeTimepoint: Day 1, 1 week, 1 month, 3 months