Assessment of the influence of intracranial space occupying lesions on the reliability of monitoring of the bispectral index for the detection of return of consciousness
Completed
- Conditions
- Er wordt gekeken naar de anesthesie bij neurochirurgische patienten met en zonder hersentumoren Er wordt niet specifiek naar de aandoening onderzoek gedaan.return of consciousness
- Registration Number
- NL-OMON33118
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
All patients: Age > 18 years
Study group: known intracranial pathology (recently obtained CT/MRI)
Control group: Neurosurgical patients without intracranial pathology
Exclusion Criteria
Patient refusal
Significantly increased intracranial pressure
Uncontrolled arterial hypertension
Significant coronary artery disease
Anticipated difficult airway
Decreased level of consciousness
Existing motor weakness dominant arm/hand
Impaired hearing
Nausea, vomiting
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To assess whether BIS values at return of consciousness are different in<br /><br>patients with or without brain tumors.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Difference between left- and rightsided BIS values in patients with<br /><br>supratentorial brain tumor during course of the study and at loss and return of<br /><br>consciousness.<br /><br>Comparison between predicted and measured propofol plasma concentrations during<br /><br>course of the study and at loss and return of consciousness.</p><br>