Biomarker Establishment for Superior Treatment of PTSD
- Conditions
- PTSD
- Registration Number
- NCT03343028
- Lead Sponsor
- Stanford University
- Brief Summary
The purpose of Biomarker Establishment for Superior Treatment of PTSD is to accelerate research on the discovery of biological, neurological and neuroimaging markers for Post- Traumatic Stress Disorder (PTSD). The investigators hope to validate and extend the network efficiency and verbal memory biomarker for PTSD. The investigators hope to learn whether there are pretreatment biological factors that can predict response to therapy. They want to do this by understanding the brain network function, relating EEG to functional magnetic resonance imaging, and application of network analysis tool.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 292
- Diagnosis of PTSD by VA clinicians and acceptance into PE or CPT treatment as part of the PCT
- Veterans of any era
- MRI safety contraindications
- Active, uncontrolled medical illness
- Acute suicidality
- Current substance dependence
- Current use of thyroid medication or active hyper/hypothyroidism
- Neurological disorder affecting the CNS Seg stroke, epilepsy, tumorW or penetrating head injury
- Use of PRN within 48 hours of the MRI/EEG
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Understanding the brain network function-neuroimaging and behavioral with Clinician-Administered PTSD Scale for DSM-5 Approximately 3 months We will be using CAPS 5
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
VA Palo Alto Health Care System (VAPAHCS)
🇺🇸Palo Alto, California, United States
New Mexico VA Health Care System
🇺🇸Albuquerque, New Mexico, United States
VA Palo Alto Health Care System (VAPAHCS)🇺🇸Palo Alto, California, United States