Experimental Human Rhinovirus Infectio

Phase 1

• Conditions: Viral infections in general, and the common cold induced by HRV-16 in particular.; MedDRA version: 14.1Level: PTClassification code 10061494Term: Rhinovirus infectionSystem Organ Class: 10021881 - Infections and infestations; Therapeutic area: Diseases [C] - Virus Diseases [C02]

• Registration Number: EUCTR2012-004938-42-NL
• Lead Sponsor: Radboud University Nijmegen Medical Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-11-13
• Study Completion: 2013-06-28
• Last Update Posted: 3 May 2021

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 0

Inclusion Criteria

- Age =18 and =35
- Healthy
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 40
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- Pregnancy or lactating
- Pre-existent lung disease, including asthma
- A history of allergic rhinitis with positive allergen skin tests
- Use of any medication
- Use of nutritional supplements / probiotics
- Use of alcohol > 5 units/day or >20 units/wk
- Use of any drugs
- Current smoker or more than 5 pack-year history
- Frequently have nosebleeds
- Recent nasal or otologic surgery
- Febrile illness or a common cold within four weeks before the HRV challenge
- Currently participating in another clinical trial

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified