NCT01685905Unknown不适用
Evaluation of the Usefulness of Interferon-γ Release Assays and Tuberculin Skin Test for Detection of Latent Mycobacterium Tuberculosis Infection in Korean Patients With Rheumatic Diseases
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- The agreement between QuantiFERON-TB Gold(QFT-G) and tuberculin skin test(TST) as a screening test for latent tuberculosis infection(LTBI)
研究概览
简要总结
The purposes of this study
- to compare the positivity of tuberculin skin test(TST) and QuantiFERON-TB Gold (QFT-G), and determine the level of agreement between two tests in patients with rheumatic diseases
- to evaluate the difference in the occurrence of active TB in patients who receive both QFT-G and TST compared with those who receive only TST for detecting of Latent tuberculosis infection(LTBI) who are candidates of TNF inhibitors.
详细描述
Study Assessment
- The positive rates of QFT-G and TST as a screening test for LTBI
- The positive rates of QFT-G and TST will be analyzed
- Additional analysis will be performed according to the type of disease
- The agreement between QFT-G and TST as a screening test for LTBI
- The agreement between QFT-G and TST will be analyzed for patients with rheumatic diseases who examined both QFT-G and TST
- Additional analysis will be performed according to the type of disease
- The correlation of the occurrence of active TB and two tests (QFT-G and TST)
- The analysis of the correlation of the occurrence of active TB and two tests will be conducted for patients who have experienced anti-TNF agents
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with rheumatic diseases who examined TST or QFT-G in Hanyang university hospital from 2004 to 2010
排除标准
- 未提供
结局指标
主要结局
The agreement between QuantiFERON-TB Gold(QFT-G) and tuberculin skin test(TST) as a screening test for latent tuberculosis infection(LTBI)
时间窗: one year
次要结局
- The correlation of the occurrence of active Tuberculosis and two tests (QuantiFERON-TB Gold (QFT-G) and tuberculosis skin test(TST))(one year)
研究者
Sang-Cheol Bae
Professor, MD, PhD, MPH
Hanyang University
研究点 (1)
Loading locations...
相似试验
已完成
4 期
Evaluation of 2 Interferon γ Assays in the Diagnosis of Latent Tuberculosis in HIV-infected Patients.ANRS EP 40 QUANTI SPOTTuberculosisHIV InfectionsNCT00647205French National Agency for Research on AIDS and Viral Hepatitis240
已完成
不适用
Detection of Latent Tuberculosis in Hemodialysis PatientsChronic Renal FailureNCT00695734University Hospital, Geneva62
已完成
4 期
QuantiFERON®-TB Gold In-Tube for the Diagnosis of Tuberculosis Infection in Contact Tracing Study.Latent Tuberculosis InfectionNCT01223534Hospital Universitari de Bellvitge871
已完成
不适用
Prognostic Value of Interferon Gamma Release Assays in Predicting Active Tuberculosis Among Individuals With, or at Risk of, Latent Tuberculosis InfectionLatent TuberculosisTuberculosisNCT01162265Public Health England10,000
已完成
不适用
Specificity Trial of the Recombinant Tuberculosis Allergen in BCG Vaccinated Healthy VolunteersTuberculosisNCT05203068National Medical Research Center of Phthisiopulmonology and Infectious Diseases150