A Longitudinal Study of Choroidal Changes Assessed With Swept-source Optical Coherence Tomography After Cataract Surgery in Eyes With Diabetic Retinopathy
试验速览
- 阶段
- 不适用
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- CVI at 3 months postoperatively
研究概览
简要总结
To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery
详细描述
To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery through the follow-up of choroidal thickness (CT) and choroidal vascularity index (CVI) using swept-source optical coherence tomography (SS-OCT) system.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged⩾40years; intraocular pressure (IOP) < 21 mm Hg in both eyes, spherical refractive error<6 diopters spherical equivalent.
排除标准
- •previous retinal surgery, glaucoma, uveitis, age-related macular degeneration, arterial or vein occlusions, macular hole, or other ocular diseases that could interfere the CT and/or CVI measurement, severe systemic diseases, such as uncontrolled hypertension, obstructive sleep apnea, etc.
结局指标
主要结局
CVI at 3 months postoperatively
时间窗: CVI was assessed 3 months after surgery.
choroidal vascularity index (CVI)was defined as the proportion of vascular area to total circumscribed area.
VD at 1 week postoperatively
时间窗: VD of the choriocapillaris was assessed 1 week after surgery.
VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid.
CVI at baseline
时间窗: CVI was assessed at baseline(within 1 week before surgery)
choroidal vascularity index(CVI) was defined as the proportion of vascular area to total circumscribed area.
CT at 3 months postoperatively
时间窗: CT was assessed at 3 months after surgery.
Choroid thickness (CT) was the thickness of the choroidal layer, CT values were obtained with the built-in software of the SS-OCT device.
VD at 1 month postoperatively
时间窗: VD of the choriocapillaris was assessed 1 month after surgery.
VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid.
CT at baseline
时间窗: CT was assessed at baseline and 1 week, 1 month, 3 month after surgery.
Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device.
VD at baseline
时间窗: VD of the choriocapillaris was assessed at baseline.
VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid.
VD at 3 months postoperatively
时间窗: VD of the choriocapillaris was assessed 3 months after surgery.
VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid
CT at 1 week postoperatively
时间窗: CT was assessed at 1 week after surgery.
Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device.
CT at 1 month postoperatively
时间窗: CT was assessed at 1 month after surgery.
Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device.
CVI at 1 week postoperatively
时间窗: CVI was assessed 1 week after surgery.
choroidal vascularity index (CVI) was defined as the proportion of vascular area to total circumscribed area.
CVI at 1 month postoperatively
时间窗: CVI was assessed 1 month after surgery.
choroidal vascularity index (CVI) was defined as the proportion of vascular area to total circumscribed area.
次要结局
- BCVA at 3 months postoperatively(BCVA was assessed 3 months after surgery.)
- IOP at 1 week postoperatively(IOP was assessed 1 week after surgery.)
- IOP at 3 months postoperatively(IOP was assessed 3 months after surgery.)
- BCVA at baseline(BCVA was assessed at baseline .)
- IOP at baseline(IOP was assessed at baseline and 1 week, 1 month, 3 month after surgery.)
- IOP at 1 month postoperatively(IOP was assessed 1 month after surgery.)