Telerehabilitation Based Motor Imagery and Action Observation Training in Multiple Sclerosis

Not Applicable

Not yet recruiting

• Conditions: Multiple Sclerosis
• Interventions: Other: Traditional rehabilitation; Other: Action observation therapy and motor imagery

• Registration Number: NCT06295601
• Lead Sponsor: Inonu University

Brief Summary

This study aims to investigate the effects of the treatment combination consisting of motor imagery and action observation therapy on balance, functional mobility, lower extremity muscle strength, fatigue and quality of life.

Detailed Description

The study population was participants with relapsing remitting multiple sclerosis. The traditional rehabilitation program consists of a joint treatment in which lower extremity strengthening and balance exercises are carried out synchronously for the experimental and control groups. Motor imagery and action observation therapy based on telerehabilitation of certain movements will be applied to the experimental group. All treatments will be carried out online via the zoom program. The treatment program will be applied 3 times a week for 6 weeks. Evaluations will be made before and after the treatment program. Assessments include balance, lower extremity muscle strength and functional mobility, fatigue, and quality of life.

Study Timeline

• Study First Submitted: 2024-02-21
• Status Verified: 2024-03
• Study First Submitted QC: 2024-03-04
• Last Update Submitted: 2024-03-04
• Study First Posted: 2024-03-06
• Last Update Posted: 2024-03-06
• Study Start: 2024-03-20
• Primary Completion: 2025-02-15
• Study Completion: 2025-08-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Being diagnosed with mulltiple sclerosis according to the McDonald criteria
• Expanded Disability Status Scale<5.5,
• Being between the ages of 18-65,
• Mini mental test score>24,
• Have a phone that can adapt to participating in a video call

Exclusion Criteria

• Having another additional neurological disease that may cause balance and coordination disorders,
• Receiving physical therapy in the last 6 months,
• Having an attack in the last 3 months
• Refusal to participate in the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental group	Traditional rehabilitation	Individuals will receive standard rehabilitation and telerehabilitation-based motor imagery and action observation therapy.
Control group	Traditional rehabilitation	Individuals will receive standard rehabilitation.
Experimental group	Action observation therapy and motor imagery	Individuals will receive standard rehabilitation and telerehabilitation-based motor imagery and action observation therapy.

Primary Outcome Measures

Name	Time	Method
Berg Balance Scale	6 weeks after baseline	Berg Balance Scale consists of a total of 14 items. Evaluation for each stage is made between 0-4. Higher score indicates better functional balance performance
Muscle strength and functional mobility	6 weeks after baseline	The participant will be asked to sit and stand up from a standard chair between 42-45 cm, with hands crossed on the chest, without support, 5 times. The time will be stopped when the participant completes the last sitting. It will be recorded in seconds.

Secondary Outcome Measures

Name	Time	Method
Fatigue Severity Scale	6 weeks after baseline	This scale consists of a total of 9 items and is scored between 0-7. \>4 points indicate fatigue
Multiple Sclerosis International Quality of Life (MusiQoL) questionnaire	6 weeks after baseline	The scale consists of 31 questions in 9 dimensions (subscales). The index score is calculated as the average of these subscale scores. All 9 dimensions and the index score are linearly transformed and standardized on a scale from 0 to 100; where 0 indicates the worst possible level of quality of life and 100 indicates the best level.