CTRI/2020/03/024184尚未招募未知
Dose Escalated Radiotherapy and Organ Preservation in Rectal Cancers (DEROP-RC) - DEROP-RC
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Clinical Stage T2-T3
- •-Histologically confirmed diagnosis of adenocarcinoma of the rectum
- •-The distance from anal verge of tumor upto 10 cm(Mid and low rectal tumors)
- •-Palpable upper limit
- •-Involving less than 2/3rd of the circumference
- •-ECOG Performance status 0-1
排除标准
- •-Recurrent rectal cancer
- •-Having pathology of signet ring cell carcinoma
- •-Evidence of distant metastases
- •-Prior pelvic radiotherapy, chemotherapy or surgery for rectal cancer
- •-Creatinine level greater than 1.5 times the upper limit of normal.
- •-Patients who are unable to undergo an MRI.
- •-Patients with a history of a prior malignancy within the past 5 years, except for adequately treated basal cell or squamous cell skin cancer.
- •-Patients with a history of any arterial thrombotic event within the past 6 months. This includes angina (stable or unstable), MI, TIA, or CVA.
- •-Other Anticancer or Experimental Therapy.
- •-Women who are pregnant or breast-feeding.
- •-Patients with any other concurrent medical or psychiatric condition or disease which would make them inappropriate candidates for entry into this study.
- •-Not willing to consent for the study
- •-Unreliable for close follow up
研究者
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