The effect of Aronia melanocarpa administration on cognitive health
- Conditions
- Cognitieve beperkingencognitionoverweigt
- Registration Number
- NL-OMON42891
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 102
Healthy individuals, age: 40-60 years, BMI 25-35 kg/m2
- History of severe cardiovascular, respiratory, urogenital, gastrointestinal/hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat). Dermatological/connective tissue, musculoskeletal, metabolic/nutritional, endocrine, neurological diseases, allergy, major surgery and /or laboratory assessments that might limit participation in or completion of the study protocol.
- Diabetes
- Use of medication that might have influence on endpoints (e.g. hypertension medication)
- Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study in the 180 days prior to the study
- Use of antibiotics in the 30 days prior to the start of the study
- Use of antioxidants, minerals and vitamin supplements available in pharmacies, drugstores, food markets or in alternative medicine
- Pregnancy, lactation
- Abuse of products (> 20 alcoholic consumptions per week and drugs)
- Smoking
- Weight gain or loss (> 3 kg in previous 3 months)
- High physical activity (>4.5 hours of running/week)
- History of any side effects towards intake of berries
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary efficady parameter is cognition, as assesed by a cognitive test<br /><br>battery. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary objectives include the assessment of BrainPort on intima-media<br /><br>thickness of the carotis, flavo-enzymes, liver function, and blood pressure. </p><br>